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Overview
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This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
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Overview
Immunohistochemistry of paraffin-embedded mouse heart using CXCR3 Antibody (STJ23303) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse skeletal muscle using CXCR3 Antibody (STJ23303) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CXCR3 antibody (STJ23303) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human liver cancer using CXCR3 Antibody (STJ23303) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CXCR3 antibody (STJ23303) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-CXCR3 antibody
Anti-CXCR3 antibody
Catalog Number:
A001033710STJ
Mfr. No.:
STJ23303
Price:
$297
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