Name: Anti-CXCR4 antibody
Price: 297.00 USD

Overview
- This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CXCR4 (NP_003458. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  C-X-C Chemokine Receptor Type 4; Cxc-R4; Cxcr-4; Fb22; Fusin; Hm89; Lcr1; Leukocyte-Derived Seven Transmembrane Domain Receptor; Lestr; Lipopolysaccharide-Associated Protein 3; Lap-3; Lps-Associated Protein 3; Npyrl; Stromal Cell-Derived Factor 1 Receptor; Sdf-1 Receptor; Cd Antigen Cd184 (Gene ID:7852; UniProt:P61073)
  
  * For research use only