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Overview
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Recognizes the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. The antibody reactswith osteoclasts, placenta, melanoma cell lines and weakly with platelets.Immunogen: Osteoclasts from osteoclastomas.
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