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Overview
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Reacts with CD11a (alpha subunit of human LFA-1), a 170-180 kDa type I transmembraneglycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils andeosinophils. Cell stimulation by chemokines or other signals leads to induction the high-affinityconformation, which supports tight binding of LFA-1 to its ligands, the intercellular adhesion moleculesICAM-1, -2, -3.Immunogen: leukocytes from a pacient suffering from a LGL-type leukaemia
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