Name: Anti-CD14 antibody
Price: 665.00 USD

- Overview
  - CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of maturemonocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharidereceptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchoredform. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-bindingprotein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structuraldifferences between lipopolysaccharides and is important for neutralization of serum allochthonouslipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bindapoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicingresults in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14dysfunction include mycobacterium chelonae infection and Croup.
    
    Please contact us at for specific academic pricing.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG2a
    
    Reactivity
    
    human
    
    Clone
    
    Tük 4
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    0.5 ml purified antibody, in Phosphate buffered saline solution containing 0.1%sodium Azide.
    
    Storage
    
    Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
    
    Concentration
    
    +/-200 µg/ml
    
    Regulatory Status
    
    RUO
    
    Antigen
    
    Monocyte Differentiation Antigen Cd14; Myeloid Cell-Specific Leucine-Rich Glycoprotein; Cd Antigen Cd14 Cleaved Into-Monocyte Differentiation Antigen Cd14-Urinary Form-Monocyte Differentiation Antigen Cd14-Membrane-Bound Form (Gene ID:929; UniProt:P08571)
    
    * For research use only
- Applications
  - Application
    
    Flow Cytometry