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Overview
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Common acute lymphoblastic leukemia antigen (CALLA/CD10) is a useful marker for thecharacterization of childhood leukemia and B cell lymphomas. This antibody reacts with antigen oflymphoblastic, Burkitt's, and follicular lymphomas; and chronic myelocytic leukemia. Also, Anti-CD10detects the antigen of glomerular epithelial cells and the brush border of the proximal tubules; thischaracteristic may be helpful in interpreting renal ontogenesis in conjunction with other markers.Other non-lymphoid cells that are reactive with CD10 are breast myoepithelial cells, bile canaliculi, neutrophils and small population of bone marrow cells, fetal small intestine epithelium, and normalfibroblasts.
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