A 39183A

A 39183A

Catalog Number:
M001342142TOK
Mfr. No.:
TOK-A109
Price:
$402
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      • Overview
        • A 39183A is factor A from the A-39183 antibiotic complex. The A-39183 antibiotic complex was isolated from the aerobic fermentation of Streptomyces (strain NRRL 12049) by Eli Lilly in 1979. This complex contains closely-related factors A, B, C, D, and E with broad-spectrum activity. The fractions can be separated by chromatography. A 39183A is a rare 9,9'-bianthryl antibiotic related to setomimycin and it acts as an ionophore. Factor A is a major component of the complex (36%), along with Factor B (46%). Factors C-E are minor, together accounting for ~ 18% of the complex.
          A 39183A is soluble in ethanol, methanol, DMF, DMSO, acetone, ethyl acetate, and chloroform. It is practically insoluble in water.

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          Background

          A 38183A acts as an ionophore, aiding the partitioning of Mg+ and Ca+ ions into organic solvents and transport of ferric ions into mitochondria.

      • Properties
        • CAS Number
          79426-51-0
          Molecular Formula
          C34H30O10
          Molecular Weight
          598.6
          Appearance
          Yellow solid
          Solubility
          Soluble in ethanol, methanol, DMF, DMSO, acetone, ethyl acetate, and chloroform. It is practically insoluble in water.
          Other Properties
          Source: Streptomyces strain NRRL 12049
          Purity Level: >95% by HPLC
          Storage
          -20°C

          * For research use only

      • Applications
        • Application Description
          Spectrum: It has broad-spectrum activity against Gram-positive and Gram-negative bacteria including anaerobic species including penicillin-resistant Staphylococcus and Streptococcus.

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