Azithromycin impurity H, EvoPure®

- Overview
  - Azithromycin impurity H, EvoPure® (3'-N-[[4-(acetylamino)phenyl]sulphonyl]-3'-N-demethylazithromycin) is one of several impurities found in Azithromycin and can be used as a reference standard for impurity profiing.
    
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    Background
    
    Azithromycin inhibits bacterial growth by binding to the 70S ribosome (specifically the 50S subunit) preventing peptide bond formation and translocation during protein synthesis. Resistance is attributed to mutations in 50S rRNA preventing binding of Azithromycin and allowing the cell to synthesize error-free proteins.
- Properties
  - Categories
    
    EvoPure® Products
    
    CAS Number
    
    612069-30-4
    
    Molecular Formula
    
    C45H77N3O15S
    
    Molecular Weight
    
    932.19
    
    Storage
    
    -20°C
    
    * For research use only