Ultrathin Phosphorylcholine Coating

This phosphorylcholine-based coating material is designed for surface modification of medical-device-related components, laboratory instruments, and consumable interfaces. The material is manufactured under controlled cleanroom conditions, with production operations managed in accordance with an ISO 13485 quality management system. Product purity is reported to exceed 99%.

The coating can form a uniform nanometer-scale surface layer, typically with a thickness of less than 50 nm. It is intended to support the development of hydrophilic, low-fouling, and blood-contacting material surfaces. The coating system is compatible with a range of commonly used substrate materials, including nickel-titanium alloy, stainless steel, silicone, TPU, PEBAX, and PVC.

Material Characteristics
• Ultra-thin coating layer: typical dry-film thickness of less than 50 nm
• Uniform surface coverage: designed to provide consistent coating formation on suitable substrates
• Broad substrate compatibility: applicable to metals, elastomers, and thermoplastic polymers, subject to substrate-specific process validation
• Surface modification capability: may help improve surface hydrophilicity and reduce nonspecific biological adhesion under relevant test conditions
• Coating stability: demonstrated retention of coating performance following .5 hours of ultrasonic cleaning under the tested conditions
Manufacturing environment: produced in a Class 10,000 cleanroom environment under an ISO 13485 quality management system

Test Information
• In internal or third-party in vitro testing, the coated surface showed a reduction in thrombus-related surface deposition of up to 99% under the specified test conditions.

Recommended Application Scope
This product is supplied as a surface-modification material for research, product development, and manufacturing applications. Potential application areas include:
• Catheters and guidewires
• Blood-contacting device components
• Interventional-device components
• Medical tubing and polymer consumables
• Laboratory fluidic components
• Instrument and consumable interfaces
Performance may vary depending on substrate type, surface pretreatment, coating process, product geometry, sterilization method, storage conditions, and intended application. Customers should perform their own process validation, biocompatibility evaluation, and regulatory assessment for the final device or product.

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