Name: Tulathromycin A
Price: 201.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Tulathromycin A binds to the 50S subunit of the bacterial ribosome, interfering with bacterial protein synthesis.
- Properties
  - CAS Number
    
    217500-96-4
    
    Molecular Formula
    
    C41H79N3O12
    
    Molecular Weight
    
    806.08
    
    Appearance
    
    White or off-white powder
    
    Solubility
    
    Soluble in DMSO and ethanol. Practically insoluble in water.
    
    Other Properties
    
    Source: Semi-synthetic
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Tulathromycin A is effective against Gram-negative bacteria with mixed bacteriostatic and bactericidal activity.
    
    Eukaryotic Cell Culture Applications: Tulathromycin A was used to assess primary DNA damage using in vitro Comet assay in isolated rat lymphocytes. Lymphocytes were treated with Tulathromycin (1-100 µM) and co-treatment with an antioxidant, catalase (100 IU/ml and 500 IU/ml). The highest concentrations of Tulathromycin (50 and 100 µM) caused significant increase of DNA damage in rat lymphocytes and catalase did not significantly reduce the DNA-damaging effect of Tulathromycin. The results of this study indicate that Tulathromycin induces genotoxic effects at high concentrations and catalase does not exert protective effect in this case (Jelena, 2015).