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Overview
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Tetracycline hydrochloride is an antibiotic that inhibits bacterial protein synthesis. Tetracycline hydrochloride binds to the 30S subunit of bacterial ribosomes and interferes with the binding of tRNA to the mRNA, preventing peptidyl transferase from forming an aminoacyl-tRNA complex on the ribosome. Consequently, tetracycline hydrochloride also inhibits bacterial growth by inhibiting protein synthesis. The mechanism of action has been found to be similar but not identical to that of chloramphenicol.Tetracycline hydrochloride binds to human neutrophils and provides electron transfer between these cells and extracellularly located bacteria, which can lead to their death. It also participates in redox reactions on the surface of polyvinylidene fluoride (PVDF), which increases its surface-enhanced Raman scattering (SERS)
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- Properties
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Overview