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TAT-CBD3A6K

TAT-CBD3A6K

Catalog Number:
P004516710LIF
Mfr. No.:
PEPTIDE-PP-150
Price:
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  • Size:
    1mg
    Quantity:
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      • Overview

        • Optimised variation of CBD3.
          TAT-CBD3A6K is an optimised variation of CBD3, the 15-amino acid peptide derived from the axonal collapsin response mediator protein 2 (CRMP-2), which is a modulator of N-type voltage-gated calcium channels (CaV2.2), conjugated to the cell penetrating motif of the HIV transduction domain protein TAT. TAT-CBD3A6K binds with greater affinity to Ca2+ channels and is more stable and less prone to unfolding than the parent peptide. TAT-CBD3A6K is anti-nociceptive in a rodent model of AIDS therapy-induced peripheral neuropathy.

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      • Properties
        • Categories
          Cell Penetrating Peptides
          Molecular Formula
          C137H250N60O32
          Molecular Weight
          3249.87
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in DMSO
          Other Properties
          Sequence: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-Arg-Ser-Arg-Leu-Lys-Glu-Leu-Arg-Gly-Val-Pro-Arg-Gly-Leu-OH,YGRKKRRQRRRARSRLKELRGVPRGL
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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