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SPDP

SPDP

Catalog Number:
CFA1108320DOJ
Mfr. No.:
S291-10
Price:
$866
  • Size:
    100 mg
    Quantity:
    Add to Cart:
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      • Overview

        • SPDP, a hetero-bifunctional reagent, is useful for bridging two different proteins, such as enzymes and antibodies. SPDP first reacts with a protein molecule through its amino groups. SPDP introduces a pyridyl disulfide moiety to the protein, which is then reduced by DTT to form thiol groups. These thiol groups then form a disulfide bond with another protein molecule thus yielding a heterodimer protein.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Cross-Linking Reagents
          CAS Number
          68181-17-9
          Molecular Formula
          C12H12N2O4S2
          Molecular Weight
          312.37
          Appearance
          Amine and sulfhydryl group cross-linking
          Purity
          ≥98.0% (HPLC)
          Storage
          0-5°C,
          Shipping
          ambient temperature

          * For research use only

      • Reference

        • 1) P. Walden, Z. A. Nagy and J. Klein, Major Histocompatibility Complex-Restricted and Unrestricted Activation of Helper T Cell Lines by Liposome-bound Antigens, J. Mol. Cell. Immunol, 1986, 2, 191.

          2) R. D. Gordon, W. E. Fieles, D. L. Schotland, R. Hogue-Angeletti and R. L. Barchi, Topographical Localization of the C-terminal Region of the Voltagedependent Sodium Channel from Electrophorus Electricus Using Antibodies Raised Against a Synthetic Peptide, Proc. Natl. Acad. Sci. USA, 1987,84, 308.

    MSDS

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