SN38 Control Set for In Vitro Studies

Our SN38 Control Set is a ready-to-use solution for in vitro research, formulated to simplify your workflow and minimize handling risks of this potent cytotoxic agent. SN38 (7-ethyl-10-hydroxycamptothecin) is a metabolite of irinotecan, a highly potent cytotoxic compound that inhibits DNA topoisomerase 1, leading to apoptosis.

This control set contains 6 tubes of a 10 µM SN38 solution in DMSO, a concentration suitable for most biological research and cell-based assays.

The 10 µM concentration is intentionally set within a safe, research-appropriate range for analytical studies, both quantitative and qualitative. Each tube is intended for a single experiment, enabling straightforward dilution (see product sheet Table 1 for suggested dilutions). The SN38 solution is pre-formulated and stable at room temperature, requiring no preparation before use or dilution.

Drug Information
Chemical name: SN38 (7-ethyl-10-hydroxycamptothecin)
Chemical formula: C22H20N2O5
Molecular weight: 392.42 Da
CAS number: 86639-52-3
Mechanism of Action: Inhibition of topoisomerase I leads to inhibition of both DNA replication and transcription.
Activities: Anti-neoplastic

Key Features of the Product
• Pre-formulated 10 µM stock in DMSO —no preparation needed.
• Convenient format: 6 single-use tubes for consistent results.
• Ideal for:
Drug screening;
Cell-viability, proliferation and cytotoxicity assays;
Other qualitative and quantitative studies;
• Sufficient volume for replicates.

Please contact us at for specific academic pricing.