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Overview
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Sitafloxacin Hydrate is a broad-spectrum fluoroquinoline antibiotic that is particularly active against Gram-positive bacteria such as a pneumococci.
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Background
Sitafloxacin has been shown to have a dual targeted mechanism of action. Other antibacterial quinolones target DNA gyrase or topoisomerase IV, but sitafloxacin targets both at a very similar rate. This double-target approach lowers the possibility of resistant strains.
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