Cefminox Sodium Hydrate

- Overview
  - Cefminox Sodium Hydrate is the sodium salt form of cefminox, a semi-synthetic, second-generation cephalosporin antibiotic. It is freely soluble in aqueous solution.We offer two forms of cefminox: Cefminox (C076)
    Cefminox Sodium Hydrate (C124)
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases. Cefminox sodium, like many cephalosporins, is resistant to β-lactamase activity.
- Properties
  - CAS Number
    
    1351813-81-4
    
    Molecular Formula
    
    C16H20N7NaO7S3 • 7H2O
    
    Molecular Weight
    
    667.67
    
    Appearance
    
    White powder
    
    Other Properties
    
    Source: Semi-synthetic
    Water Content (Karl Fischer): 18.0-20.0%
    PH: 4.5-6.0
    Assay: (On Dried Basis): 90.0-97.0%
    Heavy Metals: ≤10ppm
    Optical Rotation: +62° to +72°
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Cefminox sodium is a broad-spectrum antibiotic targeting a wide range of Gram-positive and Gram-negative microbes including anaerobes.
    
    Microbiology Applications: Because of its potent properties against anaerobes, cefminox sodium can be used in cell media culture to select against Bacteroides, Clostridium, and other susceptible anaerobic bacteria.