SAINT-DNA Transfection Reagent

SAINT-DNA Transfection Reagent

Catalog Number:
TR02558380SYN
Mfr. No.:
SD-2001-01/-02/-04/-12/-XX
Price:
$501
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      • Overview
        • DNA transfection reagent SAINT-DNA
          • An improved, PBS-compatible version of SAINT-MIX
          • Quick and easy protocol
          • Efficiencies up to 100%
          • Low toxicity
          • Serum compatible
          • Suitable for rollerbottle transfection
          • Fully synthetic transfection reagent
          • Free of animal-derived components

          The SAINT-DNA transfection reagent is a proprietary, non-toxic formulation of fully synthetic cationic and neutral lipids that forms positively charged complexes with DNA and enables highly efficient uptake of DNA into cells. A wide variety of mammalian cells can be transfected with SAINT-DNA, some cell lines with efficiencies up to 100%. The transfection procedure using SAINT-DNA is easy: just mix the reagent with your DNA, incubate and pipette the complexes onto your cells. SAINT-DNA transfection reagent (1 ml) is sufficient for up to 200 transfections in 24-well plates or up to 1000 transfections in 96-well plates.

          The SAINT transfection reagents can be produced compliant to current Good Manufacturing Practice (GMP).

          Please contact us at for specific academic pricing.

          Background

          SAINT™ delivery technology is based on a set of proprietary, entirely synthetic, cationic lipid structures which have demonstrated to be safe and non-toxic both in vitro and in vivo. Due to its cationic headgroup and amphiphilic nature, SAINT lipids readily bind to most biomolecules (DNA, RNA, and protein) and to cellular membranes, facilitating efficient uptake and release of these biomolecules inside cells. SAINT lipids have demonstrated to reach similar or much higher transfection efficiencies (depending on the cell type) than competing, well-known products for a fraction of the price.

      • Properties
        • Categories
          DNA transfection reagents
          Storage
          SAINT-DNA, stored at 4°C-7°C, is stable for at least one year after opening.

          * For Research Use Only. Not for use in diagnostic procedures.

      • Reference
        • Derfoul A, et al. “Glucocorticoids promote chondrogenic differentiation of adult human mesenchymal stem cells by enhancing expression of cartilage extracellular matrix genes.” Stem Cells 24 (2006): 1487-1495.
          van Zanten J, et al. “A nonviral carrier for targeted gene delivery to tumor cells.” Cancer Gene Ther. 11 (2004): 156-164.
          Hou L, et al. “The prolactin receptor mediates HOXA1-stimulated oncogenicity in mammary carcinoma cells.” Int. J. Oncol. 41 (2012): 2285-2295.

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