SAINT-sRNA Transfection Reagent

• An improved, PBS-compatible version of SAINT-RED
• Quick and easy protocol
• Efficient transfection using low siRNA concentrations
• Low toxicity
• Serum compatible
• Fully synthetic transfection reagent
• RNase-free production
• Suitable for high throughput screening

The SAINT-sRNA transfection reagent is a proprietary, non-toxic formulation of fully synthetic cationic and neutral lipids that forms positively charged complexes with small RNA, such as siRNA and miRNA mimics or inhibitors, and enables highly efficient delivery of small RNA into a variety of mammalian cell lines. Minimal amounts of siRNA are required for efficient down regulation of the target gene. The transfection procedure using SAINT-sRNA is easy: just mix the reagent with your siRNA or miRNA, incubate and pipette the complexes onto your cells. SAINT-sRNA transfection reagent (1 ml) is sufficient for up to 200 transfections in 24-well plates or up to 1000 transfections in 96-well plates.

The SAINT transfection reagents can be produced compliant to current Good Manufacturing Practice (GMP).

Please contact us at for specific academic pricing.

Background

SAINT™ delivery technology is based on a set of proprietary, entirely synthetic, cationic lipid structures which have demonstrated to be safe and non-toxic both in vitro and in vivo. Due to its cationic headgroup and amphiphilic nature, SAINT lipids readily bind to most biomolecules (DNA, RNA, and protein) and to cellular membranes, facilitating efficient uptake and release of these biomolecules inside cells. SAINT lipids have demonstrated to reach similar or much higher transfection efficiencies (depending on the cell type) than competing, well-known products for a fraction of the price.