RW4

RW4

Catalog Number:
P004516673LIF
Mfr. No.:
PEPTIDE-AM-152
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  • Size:
    1mg
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      • Overview

        • Antimicrobial and antifungal.
          RW4 is a short peptide containing repeating arginine (R) and tryptophan (W) residues which has been shown to possess antimicrobial and antifungal activity with low cytotoxicity. The positively charged arginine interacts with the bacterial membrane through electrostatic attraction whereas the non-polar tryptophan residue interacts with the lipid bilayer. These two properties allow RW4 to interact with the bacterial membrane, resulting in membrane destabilization and pore formation and bacterial cell death. RW4 has been shown to have enhanced activity in combination with other antimicrobial agents.

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      • Properties
        • Categories
          Antimicrobial Peptides
          Molecular Formula
          C86H91N25O8
          Molecular Weight
          1386.6
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in dilute acid and physiological buffers
          Other Properties
          Sequence: H-Arg-Trp-Arg-Trp-Arg-Trp-Arg-Trp-NH2,RWRWRWRW-NH2
          Modification: C terminal amide
          Storage
          Store dry, dark and frozen

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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