Rolitetracycline

Rolitetracycline

Catalog Number:
M001342071TOK
Mfr. No.:
TOK-R023
Price:
$231
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      • Overview
        • Rolitetracycline, launched in the late 1950s, was the first of the semi-synthetic tetracyclines. Rolitetracycline is formed by a Mannich condensation of formaldehyde and pyrrolidine with tetracycline. Rolitetracycline is a pro-drug of tetracycline, in which the pyrrolidine moiety improves bioavailability compared with tetracycline. Rolitetracycline has broad spectrum Gram positive activity in vivo, but pH instability limits use to parenteral administration. The intrinsic in vitro activity and SARs for this region of the tetracycline molecule have not been extensively investigated.

          Rolitetracycline is soluble in in water and partially soluble in ethanol and methanol.

          Please contact us at for specific academic pricing.

      • Properties
        • CAS Number
          751-97-3
          Molecular Formula
          C27H33N3O8
          Molecular Weight
          527.6
          Appearance
          Yellow to orange solid
          Storage
          -20°C

          * For research use only

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