4-Epitetracycline HCl, EvoPure®

- Overview
  - 4-Epitetracycline HCl, EvoPure® is a highly purified hydrochloride salt form of 4-Epitetracycline. Under acidic conditions, Tetracycline undergoes an epimerization at the fourth carbon, producing a mixture of Tetracycline and 4-Epitetracycline. This EvoPure product is soluble in water.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Tetracycline inhibits the growth of Gram-positive and Gram-negative bacteria by disrupting codon-anticodon interactions at the ribosome, thus blocking protein synthesis. Specifically, Tetracycline binds to the 30S ribosomal subunit and blocks the attachment of charged aminoacyl-tRNA to the A site on the ribosome, preventing peptide elongation.
- Properties
  - CAS Number
    
    23313-80-6
    
    Molecular Formula
    
    C22H24N2O8 · xHCl (lot specific)
    
    Molecular Weight
    
    444.43 g/mol (Free base. Actual molecular weight shown on lot specific certificate of analysis).
    
    Appearance
    
    Yellow Solid
    
    Other Properties
    
    Source: Synthetic
    Identification: Conforms (IR, NMR, and MS)
    Purity Level: ≥98.0% (HPLC)
    
    Storage
    
    -20°C. Protect from moisture and light
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Effective against Gram-positive and Gram-negative bacteria, and Mycoplasma.