Name: Recombinant Human/Mouse/Rat Activin A GMP Protein, CF Best Seller GMP
Price: Inquiry

- Overview
  - Structure / Form: Disulfide-linked homodimer
    Predicted Molecular Mass: 13 kDa (monomer)
    N-terminal Sequence Analysis: Gly311-Leu-Glu-(Cys)-Asp-Gly-Lys-Val-Asn-Ile
    SDS-PAGE: 14 kDa, reducing conditions; 24 kDa, non-reducing conditions
    Host Cell Protein: < 0.5 ng per µg of protein when tested by ELISA.
    Mycoplasma: Negative when tested in a ribosomal RNA hybridization assay.
    Host Cell DNA: < 0.5 ng per µg of protein when tested by ELISA.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    activin AB alpha polypeptide, Activin beta-A chain, erythroid differentiation factor, Erythroid differentiation protein, follicle-stimulating hormone-releasing protein, FSH-releasing protein, inhibin beta A chain, inhibin beta A subunit, Inhibin, beta-1
    
    Source
    
    CHO cells
    
    Purification
    
    >97%, by SDS-PAGE with silver staining.
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
    
    Storage
    
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    A minimum of 12 months when stored at ≤ -20 °C as supplied. Refer to lot specific COA for the Use by Date.
    1 month, 2 to 8 °C under sterile conditions after reconstitution.
    3 months, ≤ -20 °C under sterile conditions after reconstitution.
    
    Endotoxin
    
    <0.10 EU per 1 μg of the protein by the LAL method.
    
    Reconstitution
    
    Reconstitute at 100-500 μg/mL in sterile 4 mM HCl.
    
    Activity
    
    Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340.
    The ED50 for this effect is 0.2-1.2 ng/mL.
    The specific activity of Recombinant Human/Mouse/Rat Activin A is >1000 units/mg, which is calibrated against the human Activin A WHO reference standard (NIBSC code: 91/626).
    
    More Information
    
    UniProt
    
    P08476.2
    
    Gene ID
    
    3624 (Human); 16323 (Mouse); 29200 (Rat)
    
    * This product is intended for research use or further manufacturing only.
- Applications
  - Application
    
    Bioactivity

Datasheet

MSDS

Recombinant Human/Mouse/Rat Activin A GMP Protein Bioactivity GMP-grade Recombinant Human/Mouse/Rat Activin A (Catalog # 338‑GMP) induces hemoglobin expression in K562 human chronic myelogenous leukemia cells in a dose-dependent manner. The ED50 for this effect is 0.2‑1.2 ng/mL.

Recombinant Human/Mouse/Rat Activin A GMP Protein, CF Best Seller GMP

Recombinant Human/Mouse/Rat Activin A GMP Protein, CF Best Seller GMP

More Information

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