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Overview
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Polymyxin B2 Sulfate, EvoPure® is one of several polypeptide components of Polymyxin B Sulfate. The unique fatty acid moiety found in Polymyxin B2 is 6-methylheptanoic acid (6-MHA). Results from in vitro studies have shown marginal differences in MIC data when comparing the fractions.
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Background
Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of Gram-negative bacteria leading to lysing of the cell. Polymyxin B only needs to interact with LPS, it is not required to enter the cell.
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- Properties
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Overview