Piericidin A

- Overview
  - Piericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces species.
    
    Piericidin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
    
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    Background
    
    Piericidin A is a specific, potent inhibitor of NADH-ubiquinone oxidoreductase (Complex I) that binds to ubiquinone binding site(s). Piericidin A inhibits both mitochondrial and bacterial NADH-ubiquinone oxidoreductases, binding close to NUOD-NUOB interface.
- Properties
  - CAS Number
    
    2738-64-9
    
    Molecular Formula
    
    C25H37NO4
    
    Molecular Weight
    
    415.6
    
    Appearance
    
    Pale Yellow Oil
    
    Storage
    
    -20°C
    
    * For research use only