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Overview
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Calpain inhibitor.
PD 150606 is a cell-permeable non-peptide calpain inhibitor with Ki values for ν and m-calpains of 0.21 and 0.37 M. PD 150606 targets the calcium binding sites of calpain and possesses very high selectivity for calpains relative to other proteases, acting as a non-competitive inhibitor with regard to the substrate.
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- Properties
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Overview
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