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Puromycin Dihydrochloride

Puromycin Dihydrochloride

Catalog Number:

A004268410CAN

Mfr. No.:

AB024

Price:

$288

Size:

100 mg

Quantity:

Add to Cart:

- Overview
  - Puromycin Hydrochloride is the hydrochloride salt form of puromycin, an aminonuclease antibiotic agent isolated from the bacterium Streptomyces alboniger. Toxic to both eukaryotic and prokaryotic cells. Acting as an analog of the 3′ terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. Prevents growth of bacteria, protozoa, algae, and mammalian cells.
    
    Includes for 250 mg:
    – 250 mg Puromycin Dihydrochloride
    
    Please contact us at for specific academic pricing.
- Properties
  - CAS Number
    
    58-58-2
    
    Appearance
    
    Powder format
    
    Purity
    
    purity (HPLC): > 98%
    
    Other Properties
    
    Chemical Formula: C22H29N7O5.2HCl
    Molecular Weight: 544.44
    
    Storage
    
    -20 °C (NON Frost-Free Freezer).
    
    * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.
- Applications
  - Application Description
    
    Puromycin is widely used in cell biology as a selection antibiotic agent in mammalian cell culture systems.
    Useful in CRISPR/Cas9 mammalian gene editing by selecting for successful Cas9-induced knock-in with Puromycin resistance gene.

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