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Overview
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Metalloendopeptidase inhibitor.
Phosphoramidon is a metalloendopeptidase inhibitor originally derived from cultures of Streptomyces tanashiensis. Phosphoramidon is a potent inhibitor of thermolysin and other metallo-endopeptidases and also strongly inhibits mammalian enkephalinase but does not inhibit trypsin, papain, chymotrypsin or pepsin. Phosphoramidon has been used as a neprilysin (NEP) inhibitor to study amyloid beta (A?) uptake and degradation.
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- Properties
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Overview
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