pAAVone-sc-AAV11-CMV-EGFP

pAAVone-sc-AAV11-CMV-EGFP

Catalog Number:
VP01554661AAV
Mfr. No.:
SE023001-AAV11
Price:
$1,499
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      • Overview
        • pAAVone-sc-AAV11-CMV-EGFP is a plasmid used to produce scAAV11-CMV-EGFP using novel AAVone production system. It integrates all the AAV production necessary components, including Ad helper genes (E2A, E4orf6 and VA RNA), AAV helper genes (Rep and AAV11), and a self-complementary AAV-CMV-EGFP genome. scAAV11-CMV-EGFP viruses can be simply and efficiently produced by transfection of this single-into host cells, such us HEK 293 and HEK 293T. AAV11 is another relatively lesser-known serotype within the AAV family. Like other lesser-used AAV serotypes, it has been explored primarily in the context of understanding capsid diversity and tropism. AAV11 shares some similarities with other serotypes, but its tissue tropism and potential applications in gene therapy remain less characterized compared to more common serotypes such as AAV2, AAV8, and AAV9.

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      • Properties
        • Other Properties
          AAV Capsid: AAV11
          AAV Genome: sc-AAV-CMV-SV40Intron-EGFP-WPRE3-SV40PolyA
          AAV Genome Size: 2167 bp
          AAV Genome Type: scAAV
          ITRs: L-ITR (106 bp) + R-ITR (130 bp)
          Promoter: CMV
          Transgene: EGFP
          Plasmid Size: 10641 bp
          Bacterial Resistance(s): Kana
          Plasmid Backbone: pAAVone-sc
          Storage
          -20°C for long term (> 1 year)
          Shipping
          Dry ice.
      • Applications
        • Application Description
          pAAVone plasmids are used to produce AAVs using novel AAVone signle-plasmid AAV production system. They integrates all the AAV production necessary components, including Ad helper genes (E2A, E4orf6 and VA RNA), AAV helper genes (Rep and Cap), and AAV genome. To produce AAVs, users only need select the pAAVone plasmid carrying the corresponding capsid, clone your transgenes into it and transfect them into host cells. Pre-made pAAVone plasmids are available in the following serotypes: AAV1, AAV2, AAV2-Retro, AAV3B, AAV4, AAV5, AAV6, AAV7, AAV8, AAV9, AAV11, AAV12, AAV13, AAV-DJ, AAV11, AAVrh.74, and AAV-PHP.eB.

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