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Necrostatin-1

Necrostatin-1

Catalog Number:
I002097357UBP
Mfr. No.:
F7101
Price:
$378
  • Size:
    50 mg
    Quantity:
    Add to Cart:
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      • Overview

        • Necrostatin-1 is a potent inhibitor of necroptosis, a programmed and caspase-independent cell death mechanism. The death domain receptor-associated serine/threonine kinase RIP1 is essential for TNF-induced necrosis. Necrostatin-1 inhibits RIP1 and blocks TNFα-induced necrosis of FADD-deficient Jurkat cells with an EC50 value of 490 nM.

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      • Properties
        • Protein Name
          Cas# 4311-88-0
          Source
          Synthetic
          Formulation
          Powder
          Storage
          Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light
          Concentration
          N/A
          Molecular Weight
          259.33 g/mol

          * Research Use Only

    Datasheet
    MSDS

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