Ixazomib (MLN-2238)

Ixazomib (MLN-2238)

Catalog Number:
I002097360UBP
Mfr. No.:
F1111
Price:
$752
  • Size:
    25 mg
    Quantity:
    Add to Cart:
      • Overview
        • Ixazomib (MLN2238) (commercial name: Ninlaro®) is the first and only FDA-approved oral proteasome inhibitor for the treatment of multiple myeloma. It reversibly inhibits the chymotrypsin-like activity of proteasomes with IC50 of 3.4 nM in cell-free assays, also inhibits the caspase-like and trypsin-like activities of proteasome with IC50 of 31 and 3500 nM, respectively.

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      • Properties
        • Protein Name
          [(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridine-2-carbonyl)amino]butanoyl]amino]-3-methylbutyl]boronic acid
          Source
          Synthetic
          Formulation
          C14H19BCl2N2O4
          Storage
          Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light
          Molecular Weight
          361.03 g/mol

          * Research Use Only

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