Login / Register
0

Nalidixic Acid

Nalidixic Acid

Catalog Number:
PB01342626TOK
Mfr. No.:
TOK-N011
Price:
$189
  • Size:
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Nalidixic acid is a naphthyridone antibiotic similar in structure and mechanism to quinolones.

          Please contact us at for specific academic pricing.

          Background

          Nalidixic acid indirectly inhibits proteins synthesis by binding DNA and interfering with enzymes involved in DNA replication and transcription.

      • Properties
        • CAS Number
          389-08-2
          Molecular Formula
          C12H12N2O3
          Molecular Weight
          232.24
          Appearance
          White or off-white crystalline powder
          Solubility
          Methylene chloride: Soluble
          Water: 0.1 mg/mL
          Other Properties
          Source: Synthetic
          Assay: (On Dried Basis): ≥98.0%
          Loss on Drying: ≤0.5%
          Melting Point: 225-231°C
          Storage
          2-8°C

          * For research use only

      • Applications
        • Application Description
          Spectrum: Nalidixic acid is a broad spectrum antibiotic commonly used against bacteria responsible for urinary tract infections.

          Microbiology Applications: Nalidixic acid is commonly used in clinical in vitromicrobiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive and gram negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include: Escherichia coli 2 µg/mL - 8 µg/mL Proteus mirabilis 2.1 µg/mL - 8 µg/mL Kiianitsa et al. used TOKU-E nalidixic acid at 100 µg/mL to study DNA gyrase inhibition in E. coli K-12. "Ultrasensitive isolation, identification and quantification of DNA–protein adducts by ELISA-based RADAR assay" Media Supplements Nalidixic acid can be used as a selective agent in several types of isolation media: Columbia Blood Agar - Staphylococcus/Streptococcus selective supplement Wilkins-Chalgren Anaerobe Agar - Isolation of non-sporing anaerobes Wilkins-Chalgren Anaerobe Agar - Isolation of Gram-negative anaerobes Columbia Blood Agar - Gardnerella vaginalis Selective Supplement Listeria Enrichemnt Broth - Listeria Selective Enrichment Supplement Listeria Enrichemnt Broth - Listeria Selective Enrichment Supplements UVM I and UVM II Listeria Enrichment Broth - Modified Listeria Selective Enrichemnt Supplement Fraser Broth - Fraser Supplement Fraser Broth - Half Fraser Supplement Brucella Medium Base - Modified Brucella Selective Supplement Buffered Listeria Enrichment Broth - Listeria Selective Enrichment Supplement ChromogenicListeria Agar - ChromogenicListeria Selective Supplement ChromogenicListeria Agar - Chromogenic Listeria Differential Supplement
    Datasheet
    MSDS

    Documents

    MSDS-EU

    Susceptibility and Resistance Data

    Media Supplements PDF-MS005

    Media Supplements PDF-MS027

    Media Supplements PDF-MS028

    Media Supplements PDF-MS034

    Media Supplements PDF-MS040

    Media Supplements PDF-MS041

    Media Supplements PDF-MS044

    Media Supplements PDF-MS049

    Media Supplements PDF-MS054

    Media Supplements PDF-MS075

    Media Supplements PDF-MS076

    Media Supplements PDF-MS080

    Media Supplements PDF-MS086

    We Also Recommend

    Betulinic acid

    Betulinic acid

    Betulinic Acid

    Betulinic Acid

    $178

    Betulinic acid

    Betulinic acid

    $180

    Nalidixic Acid Sodium

    Nalidixic Acid Sodium

    $146

    Nalidixic Acid Sodium, CulturePure®

    Nalidixic Acid Sodium, CulturePure®

    $166

    Roccellic Acid

    Roccellic Acid

    $300

    Usnic acid

    Usnic acid

    $183

    Usnic acid

    Usnic acid

    $292

    Note: If you don't receive our verification email, do the following:

    • Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.