N6-Methyladenosine - Amerigo Scientific

- Overview
  - N6-methyladenosine (m6A) is a modified form of adenosine that contains a methyl group at the N6 position and has a high importance in epigenetics. Among other nucleoside modifications found in mRNA, N6-methyladenosine is the most common and abundant in eukaryotes, and is related to some cancers and viral infections (Huafei, 2020). Moreover, N6-methyladenoside has been reported to regulate RNA abundance in the SARS-CoV-2 infection (Zhang, 2021)
    
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- Properties
  - Alternative Name
    
    (-)-6-(Methylamino)purine riboside
    
    CAS Number
    
    1867-73-8
    
    Molecular Formula
    
    C11H15N5O4
    
    Molecular Weight
    
    281.27 g/mol
    
    MDL Number
    
    MFCD00005739
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Huafei et al (2020). The emerging roles of N6-methyladenosine RNA methylation in human cancers. Biomarker Research 8, 24, 1-16.
    Liu et al (2019). N6-methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication. Science, Vol. 365, Issue 6458, 1171-1176.
    Zhang et al (2021). N6-methyladenosine regulates RNA abundance of SARS-CoV-2. Cell Discovery, Nature, 7, 1, 1-4.