N6-Methyladenosine

N6-Methyladenosine

Catalog Number:
NNNA184567BIO
Mfr. No.:
NM32281
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    • Overview
      • N6-methyladenosine (m6A) is a modified form of adenosine that contains a methyl group at the N6 position and has a high importance in epigenetics. Among other nucleoside modifications found in mRNA, N6-methyladenosine is the most common and abundant in eukaryotes, and is related to some cancers and viral infections (Huafei, 2020). Moreover, N6-methyladenoside has been reported to regulate RNA abundance in the SARS-CoV-2 infection (Zhang, 2021)

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    • Properties
      • Alternative Name
        (-)-6-(Methylamino)purine riboside
        CAS Number
        1867-73-8
        Molecular Formula
        C11H15N5O4
        Molecular Weight
        281.27 g/mol
        MDL Number
        MFCD00005739
        Note
        There is no hazardous surcharge associated with this product.
        There is no special packaging charge associated with this product.

        * For research use only. Not for human or veterinary use

    • Reference
      • Huafei et al (2020). The emerging roles of N6-methyladenosine RNA methylation in human cancers. Biomarker Research 8, 24, 1-16.
        Liu et al (2019). N6-methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication. Science, Vol. 365, Issue 6458, 1171-1176.
        Zhang et al (2021). N6-methyladenosine regulates RNA abundance of SARS-CoV-2. Cell Discovery, Nature, 7, 1, 1-4.

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