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Overview
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MLN4924 is a cell-permeable and potent inhibitor of Nedd8 activating enzyme (NAE) with IC50 of 4.7 nM. At 1 - 3 uM, MLN4924 potently inhibits the activities of Cullin-based E3 ubiquitin ligases in cells as neddylation of Cullin proteins is required for activating these ubiquitin ligases.
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- Properties
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Overview
MLN4924
MLN4924
Catalog Number:
I002097684UBP
Mfr. No.:
F5150-2
Price:
$240
Size:
2 mg
Quantity:
Add to Cart: