m-dPEG®₈-amine

m-dPEG®8-amine, product number 10278, is a methyl-terminated PEG amine compound. The PEG is a water-soluble, single molecular weight PEG product with a discrete chain length (dPEG®). Carboxylic acids and their active esters react with the amino terminus to form amide bonds. Furthermore, the amino terminus reacts with aldehydes and ketones, forming Schiff bonds that are reducible to secondary amines. Uses for m-dPEG®8-amine include modification of acid-functionalized surfaces and free carboxylic acid groups on biomolecules.

Published Uses of m-dPEG®8-amine
In published scientific literature, the following applications have utilized m-dPEG®8-amine:

Development of probes for continuous real-time modification of renal function;
Surface functionalization of magnetic iron nanoparticles;
PEGylation of PAMAM dendrimers to modify cytotoxicity and transfection efficiency; and,
Surface coating of carbon nanotubes used for thermally controllable extraction and separation of peptides.

Bulk Scale Production of m-dPEG®8-amine is Available
If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

PEGylation with dPEG® Products
Conventional PEGylation reagents are disperse polymers. These PEG products consist of intractable mixtures of different chain lengths and molecular weights of polyethylene glycol. This complexity confounds the analyses of conjugates made with traditional PEGylation reagents.

Because our products have no dispersity, they provide all of the benefits of traditional PEGs without the inherent difficulties that are associated with conventional PEG products.

Please contact us at for specific academic pricing.