LZCap™ AG(3'Ma-Biotin)

LZCapTM AG(3'Ma-Biotin) is a Cap 1 analog with a Biotin label, which can be used as the capping agent for producing mRNAs in an “one-pot” process. Through T7 polymerase, mRNA with 5' end Cap 1 structure was generated by co-transcription using LZCapTM AG(3'Ma-Biotin), NTPs, and template DNA. The capped mRNA could be directly translated and expressed in cells and in vivo. mRNA capped with LZCapTM AG(3'Ma-Biotin) can be bound to streptavidin magnetic beads for biological functional exploration. Moreover, Biotin, as a common molecule in the body, is involved in various intracellular biological functions and exhibits strong binding affinity with many proteins. Biotin-labeled mRNA holds potential for exploration in biology.

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