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Overview
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LL Z1640-2 (5Z-7-oxozeaenol) is a cis-enone resorcylic acid lactone first reported in 1978 and later rediscovered as an irreversible and highly selective TAK 1 inhibitor. TAK1 is a MAPKKK involved in the p38 signalling cascade for pro-inflammation signals such as cytokines. LL Z1640-2 effectively prevents inflammation in animal models.
LL Z1640-2 is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.Please contact us at for specific academic pricing.
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- Properties
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Overview
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