Name: Lincomycin
Price: 274.00 USD

- Overview
  - Lincomycin is a lincosamide first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of antibacterial contains a rare amino acid (4-propyl-N-methylprolin) coupled to an equally rare aminomethylthio-octopyranoside sugar. Lincomycin is often incorrectly considered an aminoglycoside but it actually shares little or no structural similarity. It is effective for Gram-positive bacteria and disrupts protein synthesis.
    Lincomycin is soluble in ethanol, methanol, DMF and DMSO. Lincomycin is slightly soluble in water.
    
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    Background
    
    Lincomycin binds to the 50S ribosomal subunit and blocks bacterial protein synthesis.
- Properties
  - CAS Number
    
    154-21-2
    
    Molecular Formula
    
    C18H34N2O6S
    
    Molecular Weight
    
    406.5
    
    Appearance
    
    White solid
    
    Solubility
    
    Soluble in ethanol, methanol, DMF or DMSO. Slightly soluble in water.
    
    Other Properties
    
    Source: Streptomyces lincolnensis var. lincolnensis
    Purity Level: >99% by HPLC
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Lincomycin is effective against Gram-positive bacteria , and protozoans. It has been effective for Staphylococcus, Streptococcus, and Bacteroides fragilis.
    
    Plant Biology Applications: Lincomycin provides a powerful plant selection agent that facilitates recovery of plastid transformants. Cultured Nicotiana cells were used in vitro. Resistant cells are green while sensitive cells are white on the selective medium (Moll et al, 1990).

Datasheet

MSDS

Lincomycin

Lincomycin

Background

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