Lasalocid Sodium

Lasalocid Sodium

Catalog Number:
M001341626TOK
Mfr. No.:
TOK-L026
Price:
$241
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      • Overview
        • Lasalocid Sodium is the salt form of Lasalocid, a carboxylic polyether ionophore. The compound has anticancer properties and antibacterial activity. Lasalocid is isolated from Streptomyces lasaliensis, first reported in 1951. It is also known as a coccidiostat; developed for the treatment of coccidia in animals, it stops coccidia from reproducing.

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          Background

          As an ionophore, the compound can increase the permeability of biological (or artificial) lipid membranes to specific ions. Lasalocid Sodium is an ionophore that can form complexes with cations and transport through lipid membranes. It can also transport larger organic cations.
          In cancer studies, researchers found lasalocid induces autophagy through microtubule-associated protein 1 light chain 3 (LC-3)-II conversion. The autophagic properties were mediated by production of reactive oxygen species, confirmed by using a ROS inhibitor.

      • Properties
        • CAS Number
          25999-20-6
          Molecular Formula
          C34H53NaO8
          Molecular Weight
          612.8
          Appearance
          White powder
          Other Properties
          Source: Streptomyces lasaliensis
          Storage
          -20°C

          * For research use only

      • Applications
        • Application Description
          Spectrum: Lasalocid Sodium is effective against gram-positive bacteria and protozoa. Examples of gram-positive bacteria that are sensitive to the compound are Fusobacterium, Bifidobacterium, Eubacterium, Clostridium, and Lactobacillus species.

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