Isothiocyanobenzyl-EDTA

Isothiocyanobenzyl-EDTA

Catalog Number:
CFA1108314DOJ
Mfr. No.:
M030-10
Price:
$783
  • Size:
    10 mg
    Quantity:
    Add to Cart:
      • Overview
        • Isothiocyanobenzyl-EDTA adds EDTA moieties to proteins through their amine groups. The EDTA-tagged protein can then be labeled with heavy metal ions and radioactive metals, such as 111In and 99Tc, and used for immunoimaging.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Chelate Labeling
          CAS Number
          105394-74-9
          Molecular Formula
          C18H21N3O8S
          Molecular Weight
          439.44
          Appearance
          White to slightly yellowish-brown powder
          Purity
          ≥90.0% (HPLC)
          Storage
          -20°C
          Shipping
          ambient temperature

          * For research use only

      • Reference
        • 1) C. F. Meares and T. G. Wensel, "Metal Chelates as Probes of Biological Systems", Acc. Chem. Res., 1984, 17, 202.

          2) S. V. Deshpande, R. Subramanian, M. J. McCall, S. J. Denardo, G. L. Denardo and C. F. Meares, "Metabolism of Indium Chelates Attached to Monoclonal Antibody: Minimal Transchelation of Indium form Benzyl-EDTA Chelate in vivo", J. Nucl. Med., 1990, 31, 218.

          3) S. Mirzadeh, M. W. Brechbiel, R. W. Atcher and O. A. Gansow, "Radiometal Labeling of Immunoproteins: Covalent Linkage of 2-(4-Isothiocyanatobenzyl)diethylenetriaminepentaacetic acid Ligands to Immunoglobulin", Bioconjugate Chem., 1990, 1, 59.

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