Name: IL-2 (human) (Recombinant) (untagged)
Price: Inquiry

- Overview
  - Specific Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Interleukin-2; Aldesleukin
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Reactivity
    
    Human
    
    Purification
    
    >=95% (SDS-PAGE)
    
    Formulation
    
    Reconstitute 10µg vial with 100 µl sterile water to a concentration of 0.1mg/ml. Reconstitute 50µg vial with 100 µl sterile water to a concentration of 0.5mg/ml. Further dilute in other aqueous solutions. Lyophilized from sterile 0.1% TFA, 70% acetonitrile.
    
    Storage
    
    Short Term Storage +4°C ; Long Term Storage-20°C ;Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -80°C. Working aliquots are stable for up to 3 months when stored at -20°C.
    
    Endotoxin
    
    <0.01EU/µg protein (LAL test; Lonza).
    
    Activity
    
    Measured in a cell proliferation assay using CTLL2 cells. The ED50 for this effect is typically 0.35-1.4ng/ml.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application
    
    Functional Assay

IL-2 (human) (Recombinant) (untagged)

IL-2 (human) (Recombinant) (untagged)

We Also Recommend

IL-10 (human) (Recombinant) (untagged)

IL-10 (human):Fc (human) (Recombinant) (non-lytic)

IL-6 (human):Fc (human) (Recombinant)