Name: IL-6 (human):Fc (human) (Recombinant)
Price: Inquiry

- Overview
  - Specific Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
    
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- Properties
  - Protein Name
    
    Interleukin-6; B Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Interferon beta2; IFN-beta2
    
    Source
    
    CHO cells
    
    Type
    
    Recombinant Proteins
    
    Reactivity
    
    Human
    
    Purification
    
    >=98% (SDS-PAGE)
    
    Formulation
    
    Reconstitute 50µg vial in 50µl sterile water. Add 1X PBS to the desired protein concentration. Lyophilized from 0.2µm-filtered solution in PBS.
    
    Storage
    
    Short Term Storage +4°C ; Long Term Storage-20°C ; Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
    
    Endotoxin
    
    <0.06EU/µg protein (LAL test; Lonza).
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application
    
    Functional Assay

IL-6 (human):Fc (human) (Recombinant)

IL-6 (human):Fc (human) (Recombinant)

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