Name: IL-10 (human) (Recombinant) (untagged)
Price: Inquiry

- Overview
  - Specific Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggest the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
    
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- Properties
  - Protein Name
    
    Interleukin-10; Cytokine Synthesis Inhibitory Factor; CSIF
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Reactivity
    
    Human
    
    Purification
    
    >=95% (SDS-PAGE)
    
    Formulation
    
    Reconstitute 10µg vial with 100 µl sterile water to a concentration of 0.1mg/ml. Reconstitute 50µg vial with 100 µl sterile water to a concentration of 0.5mg/ml. Further dilute in other aqueous solutions.
    
    Storage
    
    Short Term Storage +4°C ; Long Term Storage-20°C ; Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -80°C. Working aliquots are stable for up to 3 months when stored at -20°C.
    
    Endotoxin
    
    <0.01EU/µg protein (LAL test; Lonza).
    
    Activity
    
    Immobilized human IL-10 at 10µg/ml (100µl/well) can bind Cynomolgus IL-10RA-Fc. The EC50 of Cynomolgus IL-10RA-Fc is 0.24-0.56µg/ml.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application
    
    Functional Assay

IL-10 (human) (Recombinant) (untagged)

IL-10 (human) (Recombinant) (untagged)

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