Human SLC25A4 full length protein-synthetic nanodisc

Human SLC25A4 full length protein-synthetic nanodisc

Catalog Number:
P001561705DIM
Mfr. No.:
FLP100032
Price:
$1,013
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      • Overview

        • Target: SLC25A4
          Tag: C-Flag Tag
          Synonyms: AAC1; ANT; ANT 1; ANT1; MTDPS12; MTDPS12A; PEO2; PEO3; PEOA2; T1
          Protein Families: Druggable Genome, Transmembrane
          Protein Pathways: Calcium signaling pathway, Huntingtons disease, Parkinsons disease

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          Background

          The protein functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length SLC25A4 protein has a MW of 33.1 kDa
          Expression system
          HEK293

          More Information

          UniProt
          P12235

          * For research use only.

    MSDS

    Documents

    Datasheet

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