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Overview
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Target: PLA2R1
Tag: C-Flag Tag
Synonyms: CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
Protein Families: Druggable Genome, TransmembranePlease contact us at for specific academic pricing.
Background
This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
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- Properties
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Overview