Human PLA2R1 full length protein-synthetic nanodisc

Human PLA2R1 full length protein-synthetic nanodisc

Catalog Number:
P001561753DIM
Mfr. No.:
FLP100147
Price:
$1,013
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      • Overview
        • Target: PLA2R1
          Tag: C-Flag Tag
          Synonyms: CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
          Protein Families: Druggable Genome, Transmembrane

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          Background

          This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length PLA2R1 protein has a MW of 168.6 kDa
          Expression system
          HEK293

          More Information

          UniProt
          Q13018

          * For research use only.

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