Human MRGRD-Strep full length protein-synthetic nanodisc

Human MRGRD-Strep full length protein-synthetic nanodisc

Catalog Number:
P001561627DIM
Mfr. No.:
FLP120349
Price:
$911
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      • Overview

        • Target: MRGRD
          Tag: C-Flag&Strep Tag
          Synonyms: MRGD, TGR7
          Protein Families: Transmembrane, Druggable Genome

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          Background

          May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2 ) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).[UniProtKB/Swiss-Prot Function]

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length MRGRD-Strep protein has a MW of 36.1 kDa
          Expression system
          HEK293

          More Information

          UniProt
          Q8TDS7

          * For research use only.

    MSDS

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    Datasheet

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