Name: Human CAV1 full length protein-synthetic nanodisc
Price: 1013.00 USD

- Overview
  - Target: CAV1
    Tag: C-Flag Tag
    Synonyms: BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
    Protein Families: Druggable Genome, Transmembrane
    Protein Pathways: Focal adhesion, Viral myocarditis
    
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    Background
    
    The scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
- Properties
  - Type
    
    Synthetic Nanodiscs
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
    
    Storage
    
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    
    Molecular Weight
    
    The human full length CAV1 protein has a MW of 20.3 kDa
    
    Expression system
    
    HEK293
    
    More Information
    
    UniProt
    
    Q03135
    
    * For research use only.

MSDS

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Datasheet

Human CAV1 full length protein-synthetic nanodisc

Human CAV1 full length protein-synthetic nanodisc

Background

More Information

Documents

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