H10, biotinylated

H10, biotinylated

Catalog Number:
P004516682LIF
Mfr. No.:
PEPTIDE-PP-010
Price:
$331
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • Biotinylated version of anterior gradient 2 (AGR2) binding peptide H10.
          H10, biotinylated is the N-terminal biotinylated version of the anterior gradient 2 (AGR2) binding peptide H10 (MKMQVRIYLV) which was identified by mRNA display from a complex (>1011) library. AGR2 is a cancer-associated protein and increased levels of extracellular AGR2 (eAGR2) have been correlated with poor prognosis in cancer patients, making it a potential biomarker. H10 possesses high affinity binding to AGR2 with a KD of 6.4 nM, and has been used as the capture reagent in an AGR2 ELISA. H10 can also inhibit cancer cell migration in breast and prostate cancer cell lines.

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      • Properties
        • Categories
          Biotin Labelled Peptides
          Molecular Formula
          C79H132N22O21S3
          Molecular Weight
          1822.26
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in water
          Other Properties
          Sequence: Biotin-Gly-Gly-Gly-Ser-Gly-Met-Lys-Met-Gln-Val-Arg-Ile-Tyr-Leu-Val-OH,Biotin-GGGSGMKMQVRIYLV
          Modification: Biotinylated at N terminus
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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