Name: pFYN peptide
Price: 412.00 USD

- Overview
  - Phosphorylated peptide substrate derived from FYN, a Src family kinase.
    pFYN peptide is a phosphorylated peptide substrate derived from FYN, a member of the Src family of kinases. pFyn peptide can be used in an AlphaLISA assay for the identification and optimization of allosteric STEP (striatal-enriched protein tyrosine phosphatase) ligands. STEP is a critical regulator of glutamatergic synapse function and neuronal survival, acting on targets directly involved in regulation of synaptic plasticity such as the NMDA and AMPA receptors, as well as targets regulating these receptors, such as ERK1/2, p38, FYN, and PYK2. pFYN-peptide phosphorylated peptide substrate is used in place of the endogenous STEP substrate FYN.
    
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    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Biotin Labelled Peptides
    
    Molecular Formula
    
    C115H183N32O43PS
    
    Molecular Weight
    
    2764.95
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in water
    
    Other Properties
    
    Sequence: Biotin-Gly-Leu-Ala-Arg-Leu-Ile-Glu-Asp-Asn-Glu-Tyr(H2PO3)-Thr-Ala-Arg-Gln-Gly-Ala-Lys-Phe-Pro-Ile-OH,GLARLIEDNEYTARQGAKFPI
    Modification: Biotin at N terminal glycine, tyrosine 11 is phosphorylated
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

pFYN peptide

pFYN peptide

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