GST-UbE3A (E6AP)

GST-UbE3A (E6AP)

Catalog Number:
EUL1097363UBP
Mfr. No.:
K1410
Price:
$424
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • UbE3A (also called E6AP) is a 100 kDa HECT (homologous to E6AP carboxyl terminus) domain ubiquitin ligase containing two E2 binding sites for UbcH7 and UbcH8. UbE3A was found to bind to the human papillomavirus (HPV) oncoprotein E6 and mediate ubiquitination of p53. A frameshift mutation in the UbE3A gene leads to loss of function and causes Angelman Syndrome.

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      • Properties
        • Protein Name
          AS; ANCR; E6-AP; E6AP; HPVE6A; EPVE6AP
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          100.7 kDa
          Sequence
          NCBI RefSeq: NM_000462.3

          * Research Use Only

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