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6xHis-Nedd8

6xHis-Nedd8

Catalog Number:
UULP097365UBP
Mfr. No.:
E4100
Price:
$387
  • Size:
    500 µg
    Quantity:
    Add to Cart:
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      • Overview

        • Nedd8 is an 81 amino acid Ub-like protein. It is conjugated to protein substrates in much the same way as Ub, using the E1, E2, E3 cascade. The specific E1 used is a heterodimer of APPBP1/UBA3. Two E2s have been discovered to follow called Ubc12 and Ube2F. Neddylation causes conformational change of the Cullin protein in the E3 called cullin-RING ligases (CRLs), which enhances the E3 Ub ligase activity of CRLs.

          Please contact us at for specific academic pricing.

      • Properties
        • Protein Name
          NEDD-8, NEDD 8
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          9 kDa
          Sequence
          NCBI RefSeq: NM_006156

          * Research Use Only

    Datasheet
    MSDS

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